Common Causes of Low Recovery in SPE Low recovery in solid phase extraction (SPE) is one of the most frustrating challenges analytical chemists face. When your target analytes fail to appear in expected concentrations, it’s essential to systematically identify where the problem lies. According to forensic science literature, recovery problems in SPE can be categorized […]
Understanding the Critical Factors in SPE Reproducibility Solid Phase Extraction (SPE) has revolutionized sample preparation across forensic, clinical, and environmental laboratories, offering significant advantages over traditional liquid-liquid extraction methods. As noted in forensic applications, SPE has been shown to significantly increase gas (GC) and liquid chromatography (LC) column life while reducing downtime on sensitive instruments
Sources of Particulate Contamination in SPE Cartridges Particulate contamination represents one of the most common and frustrating challenges in solid-phase extraction workflows. As an experienced product manager at Poseidon Scientific, I’ve seen firsthand how particulate matter can compromise SPE cartridge performance, leading to clogging, reduced flow rates, and inconsistent recoveries. Environmental samples frequently contain a
Understanding SPE Recovery Challenges Solid Phase Extraction (SPE) has revolutionized sample preparation across analytical laboratories, offering significant advantages over traditional liquid-liquid extraction methods. However, achieving consistent, high recovery rates (ideally exceeding 90%) can sometimes prove challenging. As a product manager at Poseidon Scientific specializing in SPE products, I’ve encountered numerous scenarios where recovery issues arise.
