Overview of Automated SPE Systems Automated Solid Phase Extraction (SPE) systems represent a significant advancement in modern laboratory workflows, transforming what was once a labor-intensive manual process into a streamlined, high-efficiency operation. As laboratories face increasing sample volumes and regulatory pressures, automated SPE workstations have become essential tools for maintaining analytical quality while improving throughput. […]
Sources of Contamination in SPE Workflows Solid Phase Extraction (SPE) contamination problems can arise from multiple sources, compromising analytical accuracy and reproducibility. According to forensic science literature, contamination issues are categorized alongside flow problems, recovery problems, and nonextraction problems as fundamental SPE troubleshooting areas. SPE Device-Related Contamination The most common contamination sources directly attributable to
The Critical Importance of Proper SPE Cartridge Conditioning Solid Phase Extraction (SPE) cartridge conditioning is the foundational step that determines the success or failure of your entire extraction process. As Dr. Xu, product manager at Poseidon Scientific, I’ve seen firsthand how proper conditioning techniques can dramatically improve recovery rates, precision, and overall method reliability. SPE
What Are Matrix Effects? Matrix effects represent one of the most significant challenges in modern analytical chemistry, particularly in LC-MS workflows. These effects occur when co-extracted components from the sample matrix interfere with the ionization process of target analytes in the mass spectrometer. As noted in the literature, “An undesirable feature of atmospheric pressure ionization-MS
