Applications

SPE cartridge extracting PFAS contaminants from environmental water samples

SPE Sample Preparation for PFAS Analysis in Environmental Water

Introduction to PFAS Contamination Concerns Per- and polyfluoroalkyl substances (PFAS) represent one of the most challenging environmental contaminants facing analytical chemists today. These synthetic chemicals, characterized by their strong carbon-fluorine bonds, have been widely used in industrial applications and consumer products for decades. Their persistence in the environment, bioaccumulation potential, and emerging evidence of health […]

SPE Sample Preparation for PFAS Analysis in Environmental Water Read More »

SPE cartridge preparation workflow for clinical toxicology analysis

LC-MS Compatible SPE Sample Preparation for Clinical Toxicology

Role of LC-MS in Clinical Toxicology Testing Liquid chromatography-mass spectrometry (LC-MS) has revolutionized clinical toxicology testing by providing unparalleled specificity, sensitivity, and throughput for drug screening and confirmation. Unlike traditional immunoassays that may suffer from cross-reactivity issues, LC-MS offers definitive identification and quantification of toxicological analytes through mass-to-charge ratio (m/z) measurements. The technique’s ability to

LC-MS Compatible SPE Sample Preparation for Clinical Toxicology Read More »

SPE cartridge extracting pharmaceutical contaminants from wastewater samples

SPE Workflow for Trace Pharmaceutical Contaminants in Wastewater

Pharmaceutical Contaminants Commonly Detected in Wastewater Wastewater analysis reveals a diverse array of pharmaceutical contaminants originating from human excretion, improper disposal, and manufacturing effluents. These compounds typically exist at trace concentrations (ng/L to μg/L) but pose significant environmental concerns due to their biological activity. Common classes include: Analgesics and Anti-inflammatories: Ibuprofen, diclofenac, naproxen, acetaminophen Antibiotics:

SPE Workflow for Trace Pharmaceutical Contaminants in Wastewater Read More »

SPE extraction workflow analyzing veterinary drug residues in food samples

SPE Sample Preparation for LC-MS Analysis of Veterinary Drugs

1. Veterinary Drugs Commonly Monitored in Food Products The analysis of veterinary drug residues in food products represents a critical component of food safety monitoring programs worldwide. These compounds span multiple therapeutic classes, each presenting unique analytical challenges for LC-MS detection. The most commonly monitored veterinary drugs include: Antibacterial Agents Sulfonamides (sulfamethazine, sulfadimethoxine), tetracyclines (oxytetracycline,

SPE Sample Preparation for LC-MS Analysis of Veterinary Drugs Read More »

SPE cartridge concentrating trace contaminants from environmental water samples

Using SPE to Concentrate Trace Contaminants in Environmental Samples

Environmental Contaminants Monitored at Trace Levels Environmental monitoring programs routinely target contaminants at part-per-billion (ppb) and part-per-trillion (ppt) concentrations. These trace-level pollutants include pesticides (triazines, organophosphates, carbamates), pharmaceuticals, industrial chemicals (PCBs, PAHs, phenols), endocrine disruptors, and heavy metals. The challenge for analytical chemists is that these compounds exist at concentrations far below the detection limits

Using SPE to Concentrate Trace Contaminants in Environmental Samples Read More »

SPE extraction of hormone compounds from blood plasma samples

SPE Sample Preparation for Hormone Analysis in Blood Plasma

1. Hormones Commonly Measured in Plasma Steroid hormone analysis in blood plasma encompasses a wide range of clinically relevant compounds that serve as biomarkers for endocrine function, reproductive health, and metabolic disorders. The most frequently measured steroid hormones include: Androgens Testosterone (free and total) Dihydrotestosterone (DHT) Androstenedione Dehydroepiandrosterone (DHEA) and its sulfate (DHEA-S) Estrogens Estradiol

SPE Sample Preparation for Hormone Analysis in Blood Plasma Read More »

SPE extraction workflow for multi residue pesticide testing

Designing SPE Workflows for Multi-Residue Pesticide Screening

Requirements for Multi-Residue Pesticide Analysis Multi-residue pesticide screening represents one of the most challenging analytical tasks in environmental and food safety testing. According to established literature, comprehensive screening workflows must address several critical requirements simultaneously. The primary objective is to detect and quantify a broad spectrum of pesticide residues at trace levels, typically in the

Designing SPE Workflows for Multi-Residue Pesticide Screening Read More »

SPE cartridge extracting drug metabolites from urine samples

SPE Cleanup of Urine Samples for Drug Metabolite Analysis

Drug Metabolites Commonly Detected in Urine Urine serves as the primary excretion pathway for drug metabolites, making it the matrix of choice for forensic toxicology, clinical monitoring, and doping control. The metabolites detected span various drug classes, each presenting unique chemical properties that influence extraction strategies. Common metabolites include benzoylecgonine (cocaine metabolite), norcodeine and normorphine

SPE Cleanup of Urine Samples for Drug Metabolite Analysis Read More »

SPE cartridge extraction of pesticide residues from drinking water samples

SPE Strategies for Sample Preparation of Pesticides in Drinking Water

Regulatory Limits for Pesticides in Drinking Water Drinking water safety is governed by stringent regulatory frameworks worldwide, with pesticide monitoring being a critical component of water quality assessment. The U.S. Environmental Protection Agency (EPA) establishes Maximum Contaminant Levels (MCLs) for specific pesticides in drinking water under the Safe Drinking Water Act. These limits are typically

SPE Strategies for Sample Preparation of Pesticides in Drinking Water Read More »

SPE cartridge cleanup of serum samples in clinical LC-MS laboratory

Best Practices for SPE Cleanup of Serum Samples in Clinical LC-MS Analysis

Common Clinical Analytes Measured by LC-MS Liquid chromatography-mass spectrometry (LC-MS) has revolutionized clinical analysis by enabling sensitive and specific detection of diverse analytes in serum samples. The technique’s versatility allows for comprehensive profiling across multiple therapeutic and diagnostic categories. Pharmaceutical Compounds LC-MS excels in therapeutic drug monitoring (TDM) for medications with narrow therapeutic windows. Common

Best Practices for SPE Cleanup of Serum Samples in Clinical LC-MS Analysis Read More »

Shopping Cart
Poseidon Scientific
Privacy Overview

This website uses cookies so that we can provide you with the best user experience possible. Cookie information is stored in your browser and performs functions such as recognising you when you return to our website and helping our team to understand which sections of the website you find most interesting and useful.