SPE Protocol for Removing Humic Substances from Environmental Water Samples
1. Nature of Humic and Fulvic Acid Interference in LC-MS Analysis Humic and fulvic acids constitute the primary components of dissolved organic matter (DOM) in environmental water samples, ranging from micrograms per liter in groundwater to milligrams per liter in surface freshwater. These complex macromolecular substances are amphiphilic in nature, containing both hydrophobic aromatic cores […]
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